Mario Flores
Licenciado en Ciencias, mención Química (Universidad Tecnológica Metropolitana UTEM, 2009)
Químico Industrial (Universidad Tecnológica Metropolitana UTEM, 2009)
Doctor en Química (Universidad de Chile, 2015)
Mi interés científico se centra en la fabricación y caracterización de materiales poliméricos biocompatibles y biodegradables y aplicables en diferentes áreas
1. Catalan-Figueroa, J.; Boisset, C. B.; Jara, M. O.; Flores, M. E.; Moreno-Villoslada, I.; Fiedler, J. L.; Morales, J. O.,A mechanistic approach for the optimization of loperamide loaded nanocarriers characterization: Diafiltration and mathematical modeling advantages. European Journal of Pharmaceutical Sciences 2018, 125, 215-222.
2. Pino-Pinto, J. P.; Oyarzun-Ampuero, F.; Orellana, S. L.; Flores, M. E.; Nishide, H.; Moreno-Villoslada, I., Aerogels containing 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin with controlled state of aggregation. Dyes and Pigments 2017,139, 193-200.
3. Flores, M. E.; Shibue, T.; Sugimura, N.; Nishide, H.; Moreno-Villoslada, I., Aggregation Number in Water/n-Hexanol Molecular Clusters Formed in Cyclohexane at Different Water/n-Hexanol/Cyclohexane Compositions Calculated by Titration 1H NMR. The Journal of Physical Chemistry B 2017,121(44), 10285-10291.
4. Flores, M. E.; Martínez, F.; Olea, A. F.; Shibue, T.; Sugimura, N.; Nishide, H.; Moreno-Villoslada, I.,Water-Induced Phase Transition in Cyclohexane/n-Hexanol/Triton X-100 Mixtures at a Molar Composition of 1/16/74 Studied by NMR. The Journal of Physical Chemistry B 2017,121(4), 876-882.
5. Díaz, C.; Catalán-Toledo, J.; Flores, M. E.; Orellana, S. L.; Pesenti, H.; Lisoni, J.; Moreno-Villoslada, I., Dispersion of the Photosensitizer 5,10,15,20-Tetrakis(4-Sulfonatophenyl)-porphyrin by the Amphiphilic Polymer Poly(vinylpirrolidone) in Highly Porous Solid Materials Designed for Photodynamic Therapy. The Journal of Physical Chemistry B 2017.
6. Coronel, A.; Catalán-Toledo, J.; Fernández-Jaramillo, H.; Godoy-Martínez, P.; Flores, M. E.; Moreno-Villoslada, I., Photodynamic action of methylene blue subjected to aromatic-aromatic interactions with poly(sodium 4-styrenesulfonate) in solution and supported in solid, highly porous alginate sponges. Dyes and Pigments 2017,147, 455-464.
7. Flores, M. E.; Shibue, T.; Sugimura, N.; Nishide, H.; Moreno-Villoslada, I., Correlation between 1H NMR chemical shifts of hydroxyl protons in n-hexanol/cyclohexane and molecular association properties investigated using density functional theory. Chemical Physics Letters 2016,644, 276-279.
8. Flores, M. E.; Garcés-Jerez, P.; Fernández, D.; Aros-Perez, G.; González-Cabrera, D.; Álvarez, E.; Cañas, I.; Oyarzun-Ampuero, F.; Moreno-Villoslada, I., Facile Formation of Redox-Active Totally Organic Nanoparticles in Water by In Situ Reduction of Organic Precursors Stabilized through Aromatic–Aromatic Interactions by Aromatic Polyelectrolytes. Macromolecular Rapid Communications 2016,37(21), 1729-1734.
9. Araya-Hermosilla, R.; Pucci, A.; Araya-Hermosilla, E.; Pescarmona, P. P.; Raffa, P.; Polgar, L. M.; Moreno-Villoslada, I.; Flores, M.; Fortunato, G.; Broekhuis, A. A.; Picchioni, F., An easy synthetic way to exfoliate and stabilize MWCNTs in a thermoplastic pyrrole-containing matrix assisted by hydrogen bonds. RSC Advances 2016,6(89), 85829-85837.
10. Araya-Hermosilla, R.; Lima, G. M. R.; Raffa, P.; Fortunato, G.; Pucci, A.; Flores, M. E.; Moreno-Villoslada, I.; Broekhuis, A. A.; Picchioni, F., Intrinsic self-healing thermoset through covalent and hydrogen bonding interactions. European Polymer Journal 2016,81, 186-197.
11. Taborga, L.; Díaz, K.; Olea, A. F.; Reyes-Bravo, P.; Flores, M. E.; Pena-Cortes, H.; Espinoza, L.,Effect of Polymer Micelles on Antifungal Activity of Geranylorcinol Compounds against Botrytis cinerea. Journal of agricultural and food chemistry 2015,63(31), 6890-6896.
12. Flores, M. E.; Sano, N.; Araya-Hermosilla, R.; Shibue, T.; Olea, A. F.; Nishide, H.; Moreno-Villoslada, I., Self-association of 5, 10, 15, 20-tetrakis-(4-sulfonatophenyl)-porphyrin tuned by poly (decylviologen) and sulfobutylether-β-cyclodextrin. Dyes and Pigments 2015,112, 262-273.
13. Flores, M. E.; Martínez, F.; Olea, A. F.; Shibue, T.; Sugimura, N.; Nishide, H.; Moreno-Villoslada, I., Stability of Water/Poly(ethylene oxide)43-b-poly(ε-caprolactone)14/Cyclohexanone Emulsions Involves Water Exchange between the Core and the Bulk. The Journal of Physical Chemistry B 2015,119(52), 15929-15937.
14. Fuenzalida, J. P.; Flores, M. E.; Móniz, I.; Feijoo, M.; Goycoolea, F.; Nishide, H.; Moreno-Villoslada, I., Immobilization of Hydrophilic Low Molecular-Weight Molecules in Nanoparticles of Chitosan/Poly(sodium 4-styrenesulfonate) Assisted by Aromatic–Aromatic Interactions. The Journal of Physical Chemistry B 2014,118(32), 9782-9791.
15. Flores, M. E.; Shibue, T.; Sugimura, N.; Nishide, H.; Martínez, F.; Olea, A. F.; Moreno-Villoslada, I., n-Hexanol association in cyclohexane studied by NMR and NIR spectroscopies. Journal of Molecular Liquids 2014,199(0), 301-308.
16. Gómez-Tardajos, M.; Pino-Pinto, J. P.; Díaz-Soto, C.; Flores, M. E.; Gallardo, A.; Elvira, C.; Reinecke, H.; Nishide, H.; Moreno-Villoslada, I., Confinement of 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin in novel poly(vinylpyrrolidone)s modified with aromatic amines. Dyes and Pigments 2013,99(3), 759-770.
17. Pizarro, G. d. C.; Marambio, O. G.; Jeria-Orell, M.; Flores, M. E.; Rivas, B. L., Amphiphilic diblock copolymers poly(2-hydroxyethylmethacrylate)-b-(N-phenylmaleimide) and poly(2-hydroxyethylmethacrylate)-b-(styrene) using the macroinitiator poly(HEMA)-Cl by ATRP: Preparation, characterization, and thermal properties. Journal of Applied Polymer Science 2010,118(6), 3649-3657.
18. Moreno-Villoslada, I.; Torres-Gallegos, C.; Araya-Hermosilla, R.; Fuenzalida, J. P.; Marambio, O. G.; Pizarro, G. d. C.; Flores, M. E.; Murakami, T.; Nishide, H., Different Models on Binding of Aromatic Counterions to Polyelectrolytes. Molecular Crystals and Liquid Crystals 2010,522(1), 136/[436]-147/[447].
19.Moreno-Villoslada, I.; Flores, M. E.; Marambio, O. G.; Pizarro, G. d. C.; Nishide, H., Polyaromatic-Anion Behavior of Different Polyelectrolytes Containing Benzenecarboxylate Units. The Journal of Physical Chemistry B 2010,114(23), 7753-7759.
Responsable:
| QUIM004 | BASES DE QUÍMICA |
| QUIM040 | BASES DE QUIMICA |
| QUIM055 | QUÍMICA ORGÁNICA |
| QUIM125 | QUÍMICA ORGANICA |
2023: Fomento a la Vinculación Internacional para Instituciones de Investigación “Red Chile-Japón de Materiales Poliméricos Avanzados: Materiales con Grupos Aromáticos Cargados para Estabilización Tintes y Degradación de Contaminantes Orgánicos” (FOVI220080). Investigador Nacional Asociado.
2021-2025: Proyecto FONDECYT Regular 1212026. “Molecular interaction between grapes flavonoids and lysyl oxidase by lysyl tyrosylquinone quinone cofactor mimicking: implications for human dermal collagen cross-linking”. Coinvestigador.
2021-2025: Proyecto FONDECYT Regular 1210968. “influence of aromatic-aromatic interactions on the formation, morphology, and thermomechanical and functional properties of foams based on copolymers of glycidyl methacrylate and sodium styrene sulfonate”. Coinvestigador.
2018-2021: Proyecto FONDECYT Iniciación 11181029. “Controllable crystallinity, mechanical properties, and degradability of materials made from poly(ethylene oxide), poly(e-caprolactone), and poly(Llactide)”. Investigador Responsable.
2018-2021: Proyecto FONDECYT Regular 1181695. “Reactions at the solid / liquid interface in porous materials containing aromatic polymers: the role of aromatic-aromatic interactions in the sequestration and photodegradation of aromatic molecules”. Coinvestigador.
2015-2018: Proyecto FONDECYT Postdoctorado 3160648. “Biomateriales diseñados a partir de copolímeros en bloque anfifílicos y obtenidos a través de electrospinning”. Investigador Responsable.
Copolímeros en bloque
Polímeros anfifílicos y agregados supramoleculares
Materiales poliméricos biocompatibles y biodegradables
COLABORADORES:
- Ignacio Moreno Villoslada (UACh)
- Javier Martinez (UACh)
- Francisca Werlinger (UACh-UChile)
- Andrés Gualdrón
- Oleksandra Trofymchuk (UChile)
- Felipe Oyarzún (UChile)
- Fonos: (56 63) 2293521
- Email: mario.flores@uach.cl
- Dirección: Laboratorio de Polímeros. Av Inés de Haverbeck Casa 11, Campus Isla Teja
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